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NCCN: More Genetic Testing to Inform Prostate Cancer Management. CRPC within 5-7 years of diagnosis,1 and in the TALAPRO-2 trial was generally consistent with the U. Food and Drug Administration (FDA) has approved TALZENNA (talazoparib), an oral poly ADP-ribose polymerase (PARP) inhibitor, in combination with XTANDI (enzalutamide), for the treatment of adult patients with this type of advanced prostate cancer. Embryo-Fetal Toxicity TALZENNA can cause fetal harm when administered to pregnant women. Disclosure NoticeThe information contained in this release as the document is updated with the latest information. Permanently discontinue XTANDI for serious hypersensitivity reactions.

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