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Serious drug interactions can occur when certain medicines are used together with lopinavir and ritonavir. Tell each of your healthcare providers about all medicines you use now, and any medicine you start or stop using.
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To make sure Kaletra is safe for you, tell your doctor if you have:

liver disease (especially hepatitis B or C);
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a personal or family history of Long QT Syndrome;
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It is not known whether Kaletra will harm an unborn baby. But HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Kaletra on the baby.
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Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
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