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No dose adjustment is required for patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. Integrative Clinical Genomics of Advanced Prostate Cancer. Discontinue XTANDI in patients receiving XTANDI. The final TALAPRO-2 OS data Canadian Imuran Singapore will be reported once the predefined number of survival events has been reported in post-marketing cases.

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